› 4jbf

X-ray diffraction
1.92Å resolution

Crystal structure of peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469.

Released:
DOI: 10.2210/pdb4jbf/pdb
Model geometry
Fit model/data
PDB entry 4jbf coloured by chain, front view.
PDB entry 4jbf coloured by chain, side view.
PDB entry 4jbf coloured by chain, top view.
Source organism: Lancefieldella parvulum DSM 20469
Entry authors: Filippova EV, Wawrzak Z, Minasov G, Shuvalova L, Kiryukhina O, Babnigg G, Rubin E, Sacchettini J, Joachimiak A, Anderson WF, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)

Function and Biology Details

Reaction catalysed: 
(GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n)-diphosphoundecaprenol + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = (GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n+1)-diphosphoundecaprenol + undecaprenyl diphosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidoglycan glycosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 482 amino acids
Theoretical weight: 50.65 KDa
Source organism: Lancefieldella parvulum DSM 20469
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C8W8H7 (Residues: 505-954; Coverage: 47%)
Gene name: Apar_1344
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PG4 1 x PG4
1 modified residue:
Ligand MSE 28 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P21
Unit cell:
a: 66.927Å b: 70.167Å c: 114.82Å
α: 90° β: 97.35° γ: 90°
R-values:
R R work R free
0.197 0.195 0.237
Expression system: Escherichia coli BL21(DE3)

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