Function and Biology Details
Reaction catalysed:
ATP + H(2)O + maltose-[maltose-binding protein](Side 1) = ADP + phosphate + maltose(Side 2) + [maltose-binding protein](Side 1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Phosphotransferase system, sugar-specific permease EIIA type 1
- ABC transporter type 1, transmembrane domain MetI-like
- Duplicated hybrid motif
- MetI-like superfamily
- ABC transporter-like, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- Nucleic acid-binding, OB-fold
- Molybdate/tungstate binding, C-terminal
8 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Enzyme IIA-maltose transport inhibitory complex (preferred)
PDBe Complex ID:
PDB-CPX-136376 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Maltose/maltodextrin transport system permease protein MalF
Molecule details ›
Chains: F, H
Length: 514 amino acids
Theoretical weight: 57.05 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 514 amino acids
Theoretical weight: 57.05 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P02916 (Residues: 1-514; Coverage: 100%)
Sequence domains:
- MalF, N-terminal region, transmembrane helices
- Maltose transport system permease protein MalF P2 domain
- Binding-protein-dependent transport system inner membrane component
Maltose/maltodextrin transport system permease protein MalG
Molecule details ›
Chains: G, I
Length: 296 amino acids
Theoretical weight: 32.25 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Binding-protein-dependent transport system inner membrane component
Structure domains: MetI-like
Length: 296 amino acids
Theoretical weight: 32.25 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P68183 (Residues: 1-296; Coverage: 100%)
Sequence domains: Binding-protein-dependent transport system inner membrane component
Structure domains: MetI-like
Maltose/maltodextrin import ATP-binding protein MalK
Molecule details ›
Chains: A, B, C, D
Length: 381 amino acids
Theoretical weight: 42.18 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 381 amino acids
Theoretical weight: 42.18 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P68187 (Residues: 1-371; Coverage: 100%)
Sequence domains:
Structure domains:
PTS system glucose-specific EIIA component
Molecule details ›
Chains: M, N, O, P
Length: 172 amino acids
Theoretical weight: 18.55 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
Structure domains: Glucose Permease (Domain IIA)
Length: 172 amino acids
Theoretical weight: 18.55 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P69783 (Residues: 1-169; Coverage: 100%)
Sequence domains: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
Structure domains: Glucose Permease (Domain IIA)
