› 4jgm

X-ray diffraction
3Å resolution

Crystal structure of RelB double mutants: Y300F/I335V

Released:
DOI: 10.2210/pdb4jgm/pdb
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PDB entry 4jgm coloured by chain, front view.
PDB entry 4jgm coloured by chain, side view.
PDB entry 4jgm coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A structural basis for selective dimerization by NF-κB RelB.
Vu D, Huang DB, Vemu A, Ghosh G
J Mol Biol 425 1934-1945 (2013)
PMID: 23485337

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170085 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor RelB Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.37 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q04863 (Residues: 277-378; Coverage: 18%)
Gene name: Relb
Sequence domains: Rel homology dimerisation domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3121
Unit cell:
a: 65.94Å b: 65.94Å c: 65.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.211 0.292
Expression system: Not provided

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Citations

5 review citations

NF-κB pathways in hematological malignancies.
Gasparini et al. (2014)
4 more

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