› 4jvy

X-ray diffraction
2.85Å resolution

Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA

Released:
DOI: 10.2210/pdb4jvy/pdb
PDB entry 4jvy coloured by chain, front view.
PDB entry 4jvy coloured by chain, side view.
PDB entry 4jvy coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Teplova M, Hafner M, Teplov D, Essig K, Tuschl T, Patel DJ
Genes Dev 27 928-40 (2013)
PMID: 23630077

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172634 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Female germline-specific tumor suppressor gld-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 196 amino acids
Theoretical weight: 22.48 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q17339 (Residues: 144-337; Coverage: 42%)
Gene names: T23G11.3, gld-1
Sequence domains:
Structure domains: K Homology domain, type 1
RNA (5'-R(P*CP*UP*AP*AP*CP*AP*A)-3') Chains: D, F
Molecule details ›
Chains: D, F
Length: 7 nucleotides
Theoretical weight: 2.19 KDa
Source organism: Caenorhabditis elegans
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3121
Unit cell:
a: 142.274Å b: 142.274Å c: 76.652Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.175 0.222
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

18 review citations

Past, present, and future of circRNAs.
Patop et al. (2019)
17 more

5 mentions without citation

Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Teplova et al. (2013)
4 more