› 4k0g

X-ray diffraction
1.4Å resolution

Crystal structure of human CLIC1 C24S mutant

Released:
DOI: 10.2210/pdb4k0g/pdb
PDB entry 4k0g coloured by chain, front view.
PDB entry 4k0g coloured by chain, side view.
PDB entry 4k0g coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Phang JM, Harrop SJ, Duff AP, Wilk KE, Curmi PMG

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126230 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chloride intracellular channel protein 1 Chain: A
Molecule details ›
Chain: A
Length: 251 amino acids
Theoretical weight: 28.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00299 (Residues: 2-241; Coverage: 100%)
Gene names: CLIC1, G6, NCC27
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2
Unit cell:
a: 82.215Å b: 82.728Å c: 42.167Å
α: 90° β: 116.43° γ: 90°
R-values:
R R work R free
0.156 0.155 0.181
Expression system: Escherichia coli BL21(DE3)

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