› 4k27

X-ray diffraction
2.35Å resolution

Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function

Released:
DOI: 10.2210/pdb4k27/pdb
PDB entry 4k27 coloured by chain, front view.
PDB entry 4k27 coloured by chain, side view.
PDB entry 4k27 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
Childs-Disney J, Yildirim I, Park H, Lohman J, Guan L, Tran T, Sarkar P, Schatz GC, Disney MD
ACS Chem. Biol. (2013)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196825 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
Myotonic Dystrophy Type 2 RNA Chain: U
Molecule details ›
Chain: U
Length: 55 nucleotides
Theoretical weight: 17.58 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MG 3 x MG
Ligand CL 6 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P41212
Unit cell:
a: 75.078Å b: 75.078Å c: 59.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.24
Expression system: Not provided

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