Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Capsid protein VP1 and RNA (preferred)
PDBe Complex ID:
PDB-CPX-182636 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (3 distinct):
RNA-directed RNA polymerase
Molecule details ›
Chains: A, E, I, M
Length: 460 amino acids
Theoretical weight: 52.34 KDa
Source organism: rhinovirus A16
Expression system: Escherichia coli
UniProt:
Structure domains:
Length: 460 amino acids
Theoretical weight: 52.34 KDa
Source organism: rhinovirus A16
Expression system: Escherichia coli
UniProt:
- Canonical:
Q82122 (Residues: 1694-2153; Coverage: 21%)
Structure domains:
