› 4k7k

X-ray diffraction
2.53Å resolution

Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation

Released:
DOI: 10.2210/pdb4k7k/pdb
PDB entry 4k7k coloured by chain, front view.
PDB entry 4k7k coloured by chain, side view.
PDB entry 4k7k coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation.
Lei HT, Bolla JR, Bishop NR, Su CC, Yu EW
J Mol Biol 426 403-11 (2014)
PMID: 24099674

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160129 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation efflux system protein CusC Chains: A, B
Molecule details ›
Chains: A, B
Length: 446 amino acids
Theoretical weight: 49.39 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P77211 (Residues: 18-457; Coverage: 100%)
Gene names: JW0561, b0572, cusC, ibeB, ylcB
Sequence domains: Outer membrane efflux protein
Structure domains: Outer membrane efflux proteins (OEP)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 62.014Å b: 104.488Å c: 72.063Å
α: 90° β: 101.06° γ: 90°
R-values:
R R work R free
0.211 0.208 0.267
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.
Alav et al. (2021)
5 more

2 mentions without citation

Heavy metal transport by the CusCFBA efflux system.
Delmar et al. (2015)
1 more