› 4kgs

X-ray diffraction
1.95Å resolution

Backbone Modifications in the Protein GB1 Loops: beta-3-Val21, beta-3-Asp40

Released:
DOI: 10.2210/pdb4kgs/pdb
PDB entry 4kgs coloured by chain, front view.
PDB entry 4kgs coloured by chain, side view.
PDB entry 4kgs coloured by chain, top view.
Source organism: Streptococcus sp. 'group G'
Primary publication:
Protein-like tertiary folding behavior from heterogeneous backbones.
Reinert ZE, Lengyel GA, Horne WS
J Am Chem Soc 135 12528-31 (2013)
PMID: 23937097

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139123 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin G-binding protein G Chains: A, B
Molecule details ›
Chains: A, B
Length: 57 amino acids
Theoretical weight: 6.21 KDa
Source organism: Streptococcus sp. 'group G'
Expression system: Not provided
UniProt:
  • Canonical: P06654 (Residues: 227-282; Coverage: 14%)
Gene name: spg
Sequence domains: B domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
1 modified residue:
Ligand B3D 2 x B3D

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: C2
Unit cell:
a: 80.657Å b: 35.66Å c: 46.531Å
α: 90° β: 120.44° γ: 90°
R-values:
R R work R free
0.176 0.174 0.217
Expression system: Not provided

Quick links

Citations

7 review citations

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns.
Horne et al. (2020)
6 more

5 mentions without citation

Detect, correct, retract: How to manage incorrect structural models.
Wlodawer et al. (2018)
4 more