› 4kk7

X-ray diffraction
1.68Å resolution

Structure of EccB1 from the type VII (ESX-1) secretion system of Mycobacterium tuberculosis.

Released:
DOI: 10.2210/pdb4kk7/pdb
PDB entry 4kk7 coloured by chain, front view.
PDB entry 4kk7 coloured by chain, side view.
PDB entry 4kk7 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Wagner JM, Chan S, Evans TJ, Kahng S, Kim J, Arbing MA, Eisenberg D, Korotkov KV
BMC Struct Biol 16 5 (2016)
PMID: 26922638

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164691 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ESX-1 secretion system protein eccB1 Chain: A
Molecule details ›
Chain: A
Length: 395 amino acids
Theoretical weight: 41.83 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand NI 4 x NI
Ligand TRS 1 x TRS
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 31.7Å b: 110.63Å c: 110.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.214
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Esx Systems and the Mycobacterial Cell Envelope: What's the Connection?
Bosserman et al. (2017)
3 more

3 mentions without citation

Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Wagner et al. (2016)
2 more