› 4kkn

X-ray diffraction
2.25Å resolution

Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704

Released:
DOI: 10.2210/pdb4kkn/pdb
PDB entry 4kkn coloured by chain, front view.
PDB entry 4kkn coloured by chain, side view.
PDB entry 4kkn coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Kumar PR, Ahmed M, Banu R, Bhosle R, Bonanno J, Calarese DA, Celikgil A, Chamala S, Chan MK, Chowdhury S, Fiser A, Garforth SJ, Scott Glenn A, Hammonds J, Hillerich B, Khafizov K, Lafleur J, Attonito J, Love JD, Patel H, Patel R, Seidel RD, Smith B, Stead M, Toro R, Casadevall A, Almo SC, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cytotoxic T-lymphocyte protein 4 Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.45 KDa
Source organism: Bos taurus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q28090 (Residues: 34-154; Coverage: 55%)
Gene names: CD152, CTLA-4, CTLA4
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2221
Unit cell:
a: 80.875Å b: 87.831Å c: 52.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.19 0.241
Expression system: Trichoplusia ni

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