› 4kw3

X-ray diffraction
2.7Å resolution

Crystal structure of the non-structural protein 1 N-terminal origin-recognition/nickase domain from the emerging human bocavirus

Released:
DOI: 10.2210/pdb4kw3/pdb
PDB entry 4kw3 coloured by chain, front view.
PDB entry 4kw3 coloured by chain, side view.
PDB entry 4kw3 coloured by chain, top view.
Source organism: Human bocavirus
Primary publication:
Structure of the NS1 protein N-terminal origin recognition/nickase domain from the emerging human bocavirus.
Tewary SK, Zhao H, Shen W, Qiu J, Tang L
J Virol 87 11487-93 (2013)
PMID: 23966383

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111977 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Initiator protein NS1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 31.16 KDa
Source organism: Human bocavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: D0EZM8 (Residues: 1-271; Coverage: 35%)
Gene name: NS1
Structure domains: Replication Protein E1; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1, APS BEAMLINE 23-ID-B
Spacegroup: P41212
Unit cell:
a: 199.804Å b: 199.804Å c: 56.456Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.207
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Human Parvoviruses.
Qiu et al. (2017)
6 more

5 mentions without citation

Structure of the NS1 protein N-terminal origin recognition/nickase domain from the emerging human bocavirus.
Tewary et al. (2013)
4 more