› 4l16

X-ray diffraction
2.8Å resolution

Crystal structure of FIGL-1 AAA domain in complex with ADP

Released:
DOI: 10.2210/pdb4l16/pdb
Model geometry
Fit model/data
PDB entry 4l16 coloured by chain, front view.
PDB entry 4l16 coloured by chain, side view.
PDB entry 4l16 coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
Peng W, Lin Z, Li W, Lu J, Shen Y, Wang C
J Biol Chem 288 29305-12 (2013)
PMID: 23979136

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127564 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fidgetin-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 36.95 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: O16299 (Residues: 261-594; Coverage: 56%)
Gene names: F32D1.1, figl-1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P65
Unit cell:
a: 113.539Å b: 113.539Å c: 58.101Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.239
Expression system: Escherichia coli

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Citations

2 review citations

Microtubule-severing enzymes: From cellular functions to molecular mechanism.
McNally et al. (2018)
1 more

2 mentions without citation

Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
Peng et al. (2013)
1 more