› 4l24

X-ray diffraction
2.7Å resolution

Crystal structure of metallo-DNA duplex containing consecutive T-Hg(II)-T base pairs

Released:
DOI: 10.2210/pdb4l24/pdb
PDB entry 4l24 coloured by chain, front view.
PDB entry 4l24 coloured by chain, side view.
PDB entry 4l24 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of metallo DNA duplex containing consecutive Watson-Crick-like T-Hg(II)-T base pairs.
Kondo J, Yamada T, Hirose C, Okamoto I, Tanaka Y, Ono A
Angew Chem Int Ed Engl 53 2385-8 (2014)
PMID: 24478025

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117771 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*GP*AP*TP*TP*TP*CP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.65 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand HG 2 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-1A
Spacegroup: P212121
Unit cell:
a: 25.5Å b: 41.27Å c: 64.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.258 0.267
Expression system: Not provided

Quick links

Citations

4 review citations

Metal-Mediated Base Pairs: From Characterization to Application.
Jash et al. (2017)
3 more

3 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
2 more