› 4l26

X-ray diffraction
1.4Å resolution

Crystal structure of DNA duplex containing consecutive T-T mispairs (Br-derivative)

Released:
DOI: 10.2210/pdb4l26/pdb
PDB entry 4l26 coloured by chain, front view.
PDB entry 4l26 coloured by chain, side view.
PDB entry 4l26 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of metallo DNA duplex containing consecutive Watson-Crick-like T-Hg(II)-T base pairs.
Kondo J, Yamada T, Hirose C, Okamoto I, Tanaka Y, Ono A
Angew Chem Int Ed Engl 53 2385-8 (2014)
PMID: 24478025

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*(CBR)P*GP*AP*TP*TP*TP*CP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.73 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CBR 2 x CBR

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21
Unit cell:
a: 27.36Å b: 39.31Å c: 30.46Å
α: 90° β: 99.41° γ: 90°
R-values:
R R work R free
0.232 0.232 0.266
Expression system: Not provided

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Citations

5 review citations

Metal-Mediated Base Pairs: From Characterization to Application.
Jash et al. (2017)
4 more