› 4l8e

X-ray diffraction
1.7Å resolution

Crystal structure of a glutathione transferase family member from xenorhabdus nematophila, target efi-507418, with two gsh per subunit

Released:
DOI: 10.2210/pdb4l8e/pdb
PDB entry 4l8e coloured by chain, front view.
PDB entry 4l8e coloured by chain, side view.
PDB entry 4l8e coloured by chain, top view.
Source organism: Xenorhabdus nematophila ATCC 19061
Entry authors: Vetting MW, Toro R, Bhosle R, Al Obaidi NF, Morisco LL, Wasserman SR, Sojitra S, Stead M, Washington E, Scott Glenn A, Chowdhury S, Evans B, Hammonds J, Hillerich B, Love J, Seidel RD, Imker HJ, Gerlt JA, Armstrong RN, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112565 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase enzyme with thioredoxin-like domain Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 26.92 KDa
Source organism: Xenorhabdus nematophila ATCC 19061
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D3VKV1 (Residues: 1-213; Coverage: 100%)
Gene names: XNC1_3157, yfcG
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand GSH 3 x GSH
Ligand CL 1 x CL
Ligand MES 1 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P6522
Unit cell:
a: 65.331Å b: 65.331Å c: 213.919Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.152 0.151 0.176
Expression system: Escherichia coli BL21(DE3)

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