› 4l9a

X-ray diffraction
2Å resolution

Crystal structure of Smu.1393c from cariogenic pathogen Streptococcus mutans

Released:
DOI: 10.2210/pdb4l9a/pdb
PDB entry 4l9a coloured by chain, front view.
PDB entry 4l9a coloured by chain, side view.
PDB entry 4l9a coloured by chain, top view.
Source organism: Streptococcus mutans UA159
Primary publication:
Structural and functional characterization of a novel α/β hydrolase from cariogenic pathogen Streptococcus mutans.
Wang Z, Li L, Su XD
Proteins 82 695-700 (2014)
PMID: 24115105

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-184200 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AB hydrolase-1 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 292 amino acids
Theoretical weight: 33.4 KDa
Source organism: Streptococcus mutans UA159
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DTF4 (Residues: 1-275; Coverage: 100%)
Gene name: SMU_1393c
Sequence domains: alpha/beta hydrolase fold
Structure domains: alpha/beta hydrolase

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P21
Unit cell:
a: 43.504Å b: 135.958Å c: 51.568Å
α: 90° β: 92.51° γ: 90°
R-values:
R R work R free
0.167 0.164 0.205
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Structural genomics studies of human caries pathogen Streptococcus mutans.
Li et al. (2014)

1 mention without citation

Harnessing Nature's Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins.
Jacob et al. (2016)