Function and Biology Details
Reactions catalysed:
Myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + NADH
1D-chiro-inositol + NAD(+) = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150888 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase
Molecule details ›
Chain: A
Length: 337 amino acids
Theoretical weight: 37.65 KDa
Source organism: Bacillus subtilis subsp. subtilis str. 168
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 337 amino acids
Theoretical weight: 37.65 KDa
Source organism: Bacillus subtilis subsp. subtilis str. 168
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P26935 (Residues: 1-337; Coverage: 98%)
Sequence domains:
- Oxidoreductase family, NAD-binding Rossmann fold
- Oxidoreductase family, C-terminal alpha/beta domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CLSI BEAMLINE 08ID-1
Spacegroup:
I222
Expression system: Escherichia coli BL21(DE3)
