Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117782 (preferred)
Entry contents:
1 distinct polypeptide molecule
3 distinct DNA molecules
3 distinct DNA molecules
Macromolecules (4 distinct):
Crossover junction endodeoxyribonuclease RuvC
Molecule details ›
Chains: A, B
Length: 169 amino acids
Theoretical weight: 18.07 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
Sequence domains: Crossover junction endodeoxyribonuclease RuvC
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Length: 169 amino acids
Theoretical weight: 18.07 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
- Canonical:
Q5SJC4 (Residues: 1-166; Coverage: 100%)
Sequence domains: Crossover junction endodeoxyribonuclease RuvC
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P3221
Expression systems:
- Escherichia coli
- Not provided
