› 4lhr

X-ray diffraction
1.5Å resolution

Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis

Released:
DOI: 10.2210/pdb4lhr/pdb
PDB entry 4lhr coloured by chain, front view.
PDB entry 4lhr coloured by chain, side view.
PDB entry 4lhr coloured by chain, top view.
Source organism: Burkholderia thailandensis E264
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyuridine 5'-triphosphate nucleotidohydrolase Chain: A
Molecule details ›
Chain: A
Length: 156 amino acids
Theoretical weight: 16.83 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2T0H6 (Residues: 1-148; Coverage: 100%)
Gene names: BTH_I0767, dut
Sequence domains: dUTPase
Structure domains: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A

Ligands and Environments

1 bound ligand:
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P63
Unit cell:
a: 84.36Å b: 84.36Å c: 54.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.118 0.117 0.135
Expression system: Escherichia coli

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