› 4lku

X-ray diffraction
1.45Å resolution

Structure of the C-terminal domain of the E. coli mechanosensitive channel of large conductance

Released:
DOI: 10.2210/pdb4lku/pdb
Model geometry
Fit model/data
PDB entry 4lku coloured by chain, front view.
PDB entry 4lku coloured by chain, side view.
PDB entry 4lku coloured by chain, top view.
Source organism: Escherichia coli DH1
Primary publication:
Structure and stability of the C-terminal helical bundle of the E. coli mechanosensitive channel of large conductance.
Walton TA, Rees DC
Protein Sci 22 1592-601 (2013)
PMID: 24038743

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Large-conductance mechanosensitive channel Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 29 amino acids
Theoretical weight: 3.24 KDa
Source organism: Escherichia coli DH1
Expression system: Not provided
UniProt:
  • Canonical: P0A742 (Residues: 108-136; Coverage: 21%)
Gene names: JW3252, b3291, mscL, yhdC

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 32.25Å b: 55.12Å c: 32.85Å
α: 90° β: 93.58° γ: 90°
R-values:
R R work R free
0.172 0.169 0.225
Expression system: Not provided

Quick links

Citations

2 review citations

Roles of Bacterial Mechanosensitive Channels in Infection and Antibiotic Susceptibility.
Sidarta et al. (2022)
1 more

5 mentions without citation

MscL: channeling membrane tension.
Walton et al. (2015)
4 more

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO