› 4lmz

X-ray diffraction
2.78Å resolution

Structural insight into RNA recognition by RRM1+2 domain of human ETR-3 protein

Released:
DOI: 10.2210/pdb4lmz/pdb
PDB entry 4lmz coloured by chain, front view.
PDB entry 4lmz coloured by chain, side view.
PDB entry 4lmz coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bhatt H, Manickam Y, Bhavesh NS

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131892 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
CUGBP Elav-like family member 2 Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95319 (Residues: 36-211; Coverage: 35%)
Gene names: BRUNOL3, CELF2, CUGBP2, ETR3, NAPOR
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
RNA (5'-R(*GP*CP*UP*GP*CP*GP*UP*AP*UP*UP*GP*UP*UP*UP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 15 nucleotides
Theoretical weight: 4.76 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: I222
Unit cell:
a: 47.006Å b: 70.134Å c: 133.064Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.244 0.292
Expression systems:
  • Escherichia coli
  • Not provided

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