› 4mbr

X-ray diffraction
3.65Å resolution

3.65 Angstrom Crystal Structure of Serine-rich Repeat Protein (Srr2) from Streptococcus agalactiae

Released:
DOI: 10.2210/pdb4mbr/pdb
PDB entry 4mbr coloured by chain, front view.
PDB entry 4mbr coloured by chain, side view.
PDB entry 4mbr coloured by chain, top view.
Source organism: Streptococcus agalactiae
Primary publication:
Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae.
Seo HS, Minasov G, Seepersaud R, Doran KS, Dubrovska I, Shuvalova L, Anderson WF, Iverson TM, Sullam PM
J Biol Chem 288 35982-96 (2013)
PMID: 24165132

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gram-positive cocci surface proteins LPxTG domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 38.48 KDa
Source organism: Streptococcus agalactiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q49RA6 (Residues: 213-548; Coverage: 28%)
Sequence domains: Bacterial Ig domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P41212
Unit cell:
a: 97.598Å b: 97.598Å c: 173.269Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.213 0.241
Expression system: Escherichia coli BL21(DE3)

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Citations

17 review citations

Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion.
Dando et al. (2014)
16 more

5 mentions without citation

Isopeptide bond in collagen- and fibrinogen-binding MSCRAMMs.
Sridharan et al. (2016)
4 more