› 4mdv

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111372 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 42.82 KDa
Source organism: Schistosoma mansoni
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C4QH88 (Residues: 1-365; Coverage: 100%)
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 13 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P21
Unit cell:
a: 67.822Å b: 88.486Å c: 68.465Å
α: 90° β: 111.18° γ: 90°
R-values:
R R work R free
0.194 0.19 0.257
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control.
Leow et al. (2015)
1 more

2 mentions without citation

Spatial arrangement of proteins in planar and curved membranes by PPM 3.0.
Lomize et al. (2022)
1 more