› 4mo3

X-ray diffraction
1.7Å resolution

Crystal Structure of Porcine C2 Domain of Blood Coagulation Factor VIII

Released:
DOI: 10.2210/pdb4mo3/pdb
PDB entry 4mo3 coloured by chain, front view.
PDB entry 4mo3 coloured by chain, side view.
PDB entry 4mo3 coloured by chain, top view.
Source organism: Sus scrofa
Entry authors: Spiegel PC, Brison C

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146106 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulation factor VIII Chain: M
Molecule details ›
Chain: M
Length: 177 amino acids
Theoretical weight: 19.9 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P12263 (Residues: 1971-2129; Coverage: 8%)
Gene names: CF8, F8
Sequence domains: F5/8 type C domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: I222
Unit cell:
a: 49.07Å b: 68.94Å c: 105.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.175 0.209
Expression system: Escherichia coli

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