› 4msb

X-ray diffraction
1.55Å resolution

RNA 10mer duplex with two 2'-5'-linkages

Released:
DOI: 10.2210/pdb4msb/pdb
PDB entry 4msb coloured by chain, front view.
PDB entry 4msb coloured by chain, side view.
PDB entry 4msb coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Sheng J, Li L, Engelhart AE, Gan J, Wang J, Szostak JW
Proc Natl Acad Sci U S A 111 3050-5 (2014)
PMID: 24516151

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196837 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA 10mer duplex with two 2'-5'-linkages Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 10 nucleotides
Theoretical weight: 3.21 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SR 7 x SR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1, ALS BEAMLINE 8.2.2
Spacegroup: C2
Unit cell:
a: 96.15Å b: 25.893Å c: 69.722Å
α: 90° β: 112.61° γ: 90°
R-values:
R R work R free
0.185 0.182 0.247
Expression system: Not provided

Quick links

Citations

8 review citations

Circular RNAs as Therapeutic Agents and Targets.
Holdt et al. (2018)
7 more

9 mentions without citation

Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Sheng et al. (2014)
8 more