› 4mt6

X-ray diffraction
5.5Å resolution

Crystal structure of closed inactive collybistin

Released:
DOI: 10.2210/pdb4mt6/pdb
PDB entry 4mt6 coloured by chain, front view.
PDB entry 4mt6 coloured by chain, side view.
PDB entry 4mt6 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N
EMBO J 33 2113-33 (2014)
PMID: 25082542

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193037 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 9 Chain: A
Molecule details ›
Chain: A
Length: 456 amino acids
Theoretical weight: 54.08 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9QX73 (Residues: 1-456; Coverage: 93%)
Gene name: Arhgef9
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: I213
Unit cell:
a: 217.259Å b: 217.259Å c: 217.259Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.237 0.282
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

The cellular and molecular landscape of neuroligins.
Bemben et al. (2015)
15 more

7 mentions without citation

A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Soykan et al. (2014)
6 more