4myo

X-ray diffraction
2.7Å resolution

Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
PDBe Complex ID:
PDB-CPX-150860 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Virginiamycin A acetyltransferase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 214 amino acids
Theoretical weight: 24.32 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26839 (Residues: 7-219; Coverage: 97%)
Gene name: vat
Sequence domains: Bacterial transferase hexapeptide (six repeats)
Structure domains: Hexapeptide repeat proteins

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2221
Unit cell:
a: 91.836Å b: 184.037Å c: 96.909Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.19 0.254
Expression system: Escherichia coli BL21(DE3)