› 4ncd

X-ray diffraction
2.04Å resolution

Crystal Structure of Class 5 Fimbriae Chaperone CfaA

Released:
DOI: 10.2210/pdb4ncd/pdb
PDB entry 4ncd coloured by chain, front view.
PDB entry 4ncd coloured by chain, side view.
PDB entry 4ncd coloured by chain, top view.
Source organism: Escherichia coli P0301867.5
Primary publication:
Structure of CfaA Suggests a New Family of Chaperones Essential for Assembly of Class 5 Fimbriae.
Bao R, Fordyce A, Chen YX, McVeigh A, Savarino SJ, Xia D
PLoS Pathog. 10 e1004316 (2014)
PMID: 25122114

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gram-negative pili assembly chaperone, N-terminal domain protein Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 28.33 KDa
Source organism: Escherichia coli P0301867.5
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 102.606Å b: 28.582Å c: 90.716Å
α: 90° β: 118.89° γ: 90°
R-values:
R R work R free
0.221 0.217 0.256
Expression system: Escherichia coli

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Citations

1 review citation

Classical chaperone-usher (CU) adhesive fimbriome: uropathogenic Escherichia coli (UPEC) and urinary tract infections (UTIs).
Behzadi P. (2020)
4 other articles

4 mentions without citation

Structure of CfaA suggests a new family of chaperones essential for assembly of class 5 fimbriae.
Bao et al. (2014)
3 more