› 4nj8

X-ray diffraction
1.6Å resolution

Crystal structure of the human ANKS3 SAM Domain L52A mutant

Released:
DOI: 10.2210/pdb4nj8/pdb
PDB entry 4nj8 coloured by chain, front view.
PDB entry 4nj8 coloured by chain, side view.
PDB entry 4nj8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Leettola CN, Knight MJ, Cascio D, Hoffman S, Bowie JU
BMC Struct Biol 14 17 (2014)
PMID: 24998259

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180608 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ankyrin repeat and SAM domain-containing protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 7.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ZW76 (Residues: 421-490; Coverage: 11%)
Gene names: ANKS3, KIAA1977
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41
Unit cell:
a: 71.89Å b: 71.89Å c: 33.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.218
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.
Garcia-Gonzalo et al. (2017)
3 more

1 mention without citation

Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Leettola et al. (2014)