› 4nkj

X-ray diffraction
2.45Å resolution

Structure of influenza B virus hemagglutinin at membrane fusion pH

Released:
DOI: 10.2210/pdb4nkj/pdb
PDB entry 4nkj coloured by chain, front view.
PDB entry 4nkj coloured by chain, side view.
PDB entry 4nkj coloured by chain, top view.
Source organism: Influenza B virus (B/Texas/3394/2013)
Primary publication:
Structural insights into the membrane fusion mechanism mediated by influenza virus hemagglutinin.
Ni F, Chen X, Shen J, Wang Q
Biochemistry 53 846-54 (2014)
PMID: 24433110

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.21 KDa
Source organism: Influenza B virus (B/Texas/3394/2013)
Expression system: Escherichia coli
UniProt:
  • Canonical: S5DRP1 (Residues: 392-541; Coverage: 26%)
Gene name: HA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: R32
Unit cell:
a: 48.18Å b: 48.18Å c: 354.895Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.255 0.268
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Mechanisms of influenza viral membrane fusion.
Blijleven et al. (2016)
2 more

4 mentions without citation

α/β coiled coils.
Hartmann et al. (2016)
3 more