4npq

X-ray diffraction
4.35Å resolution

The resting-state conformation of the GLIC ligand-gated ion channel

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-181806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proton-gated ion channel Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 318 amino acids
Theoretical weight: 36.35 KDa
Source organism: Gloeobacter violaceus PCC 7421
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7NDN8 (Residues: 44-359; Coverage: 100%)
Gene names: glr4197, glvI
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 131.533Å b: 384.095Å c: 148.439Å
α: 90° β: 98.47° γ: 90°
R-values:
R R work R free
0.24 0.24 0.244
Expression system: Escherichia coli BL21(DE3)