Function and Biology Details
Reactions catalysed:
(R)-malate = maleate + H(2)O
(1a) (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H(2)O
(R)-2-methylmalate = 2-methylmaleate + H(2)O
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
- Aconitase family, 4Fe-4S cluster binding site
- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
- Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic
- 3-Isopropylmalate dehydratase, catalytic domain
- Homoaconitase/3-isopropylmalate dehydratase, large subunit
- Isopropylmalate dehydratase and related enzymes
- Aconitase, iron-sulfur domain
1 more domain
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-160501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isopropylmalate/citramalate isomerase large subunit
Molecule details ›
Chains: A, B
Length: 443 amino acids
Theoretical weight: 48.2 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli
UniProt:
Sequence domains: Aconitase family (aconitate hydratase)
Structure domains: Aconitase, domain 3
Length: 443 amino acids
Theoretical weight: 48.2 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli
UniProt:
- Canonical:
P81291 (Residues: 1-424; Coverage: 100%)
Sequence domains: Aconitase family (aconitate hydratase)
Structure domains: Aconitase, domain 3
