› 4nsk

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 ALTERED PEPTIDE ligand V3P

Released:
DOI: 10.2210/pdb4nsk/pdb
PDB entry 4nsk coloured by chain, front view.
PDB entry 4nsk coloured by chain, side view.
PDB entry 4nsk coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Allerbring EB, Duru AD, Uchtenhagen H, Mazumdar PA, Badia-Martinez D, Madhurantakam C, Sandalova T, Nygren P, Achour A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135010 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, D-B alpha chain Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 32.09 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01899 (Residues: 25-300; Coverage: 82%)
Gene name: H2-D1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Pre-glycoprotein polyprotein GP Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.04 KDa

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2
Unit cell:
a: 90.46Å b: 108.54Å c: 57.39Å
α: 90° β: 122.43° γ: 90°
R-values:
R R work R free
0.219 0.216 0.283
Expression system: Escherichia coli

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