› 4nt1

X-ray diffraction
1.8Å resolution

Crystal structure of apo-form of Arabidopsis ACD11 (accelerated-cell-death 11) at 1.8 Angstrom resolution

Released:
DOI: 10.2210/pdb4nt1/pdb
PDB entry 4nt1 coloured by chain, front view.
PDB entry 4nt1 coloured by chain, side view.
PDB entry 4nt1 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels.
Simanshu DK, Zhai X, Munch D, Hofius D, Markham JE, Bielawski J, Bielawska A, Malinina L, Molotkovsky JG, Mundy JW, Patel DJ, Brown RE
Cell Rep 6 388-99 (2014)
PMID: 24412362

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130276 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Accelerated cell death 11 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 207 amino acids
Theoretical weight: 22.84 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O64587 (Residues: 1-206; Coverage: 100%)
Gene names: ACD11, At2g34690, T29F13.10
Sequence domains: Glycolipid transfer protein (GLTP)
Structure domains: Glycolipid transfer protein

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
1 modified residue:
Ligand KCX 4 x KCX

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 70.756Å b: 77.014Å c: 154.716Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.213
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Lipid signalling in plant responses to abiotic stress.
Hou et al. (2016)
15 more

2 mentions without citation

Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels.
Simanshu et al. (2014)
1 more