› 4ntz

X-ray diffraction
1.69Å resolution

Crystal structure of Adenylate kinase from Streptococcus pneumoniae

Released:
DOI: 10.2210/pdb4ntz/pdb
PDB entry 4ntz coloured by chain, front view.
PDB entry 4ntz coloured by chain, side view.
PDB entry 4ntz coloured by chain, top view.
Source organism: Streptococcus pneumoniae D39
Primary publication:
Adenylate kinase from Streptococcus pneumoniae is essential for growth through its catalytic activity.
Thach TT, Luong TT, Lee S, Rhee DK
FEBS Open Bio 4 672-82 (2014)
PMID: 25180151

Function and Biology Details

Reaction catalysed: 
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170113 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 24.16 KDa
Source organism: Streptococcus pneumoniae D39
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04ML5 (Residues: 1-212; Coverage: 100%)
Gene names: SPD_0214, adk
Sequence domains: Adenylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P21
Unit cell:
a: 44.22Å b: 53.7Å c: 50.87Å
α: 90° β: 114.46° γ: 90°
R-values:
R R work R free
0.186 0.184 0.222
Expression system: Escherichia coli

Quick links

Citations

7 citation in other articles

Impact of cellular health conditions on the protein folding state in mammalian cells.
Inomata et al. (2017)
6 more

4 mentions without citation

Adenylate kinase from Streptococcus pneumoniae is essential for growth through its catalytic activity.
Thach et al. (2014)
3 more