› 4nxa

X-ray diffraction
1.6Å resolution

SPERM WHALE MYOGLOBIN UNDER XENON PRESSURE 30 Bar

Released:
DOI: 10.2210/pdb4nxa/pdb
PDB entry 4nxa coloured by chain, front view.
PDB entry 4nxa coloured by chain, side view.
PDB entry 4nxa coloured by chain, top view.
Source organism: Physeter catodon
Primary publication:
Crystallographic studies with xenon and nitrous oxide provide evidence for protein-dependent processes in the mechanisms of general anesthesia.
Abraini JH, Marassio G, David HN, Vallone B, Prangé T, Colloc'h N
Anesthesiology 121 1018-27 (2014)
PMID: 25211169

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myoglobin Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.37 KDa
Source organism: Physeter catodon
UniProt:
  • Canonical: P02185 (Residues: 1-154; Coverage: 100%)
Gene name: MB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

4 bound ligands:
Ligand HEM 1 x HEM
Ligand ZN 2 x ZN
Ligand SO4 3 x SO4
Ligand XE 5 x XE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P21
Unit cell:
a: 35.37Å b: 30.717Å c: 63.583Å
α: 90° β: 104.48° γ: 90°
R-values:
R R work R free
0.186 0.185 0.202

Quick links

Citations

3 review citations

Neuroglobin: From structure to function in health and disease.
Ascenzi et al. (2016)
2 more

2 mentions without citation

Xenon-Protein Interactions: Characterization by X-Ray Crystallography and Hyper-CEST NMR.
Roose et al. (2018)
1 more