› 4nxw

X-ray diffraction
2.55Å resolution

Crystal structure of the cytosolic domain of human MiD51

Released:
DOI: 10.2210/pdb4nxw/pdb
PDB entry 4nxw coloured by chain, front view.
PDB entry 4nxw coloured by chain, side view.
PDB entry 4nxw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
Richter V, Palmer CS, Osellame LD, Singh AP, Elgass K, Stroud DA, Sesaki H, Kvansakul M, Ryan MT
J Cell Biol 204 477-86 (2014)
PMID: 24515348

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192505 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial dynamics protein MIEF1 Chain: A
Molecule details ›
Chain: A
Length: 342 amino acids
Theoretical weight: 38.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NQG6 (Residues: 119-463; Coverage: 73%)
Gene names: MID51, MIEF1, SMCR7L
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 57.534Å b: 57.534Å c: 253.749Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.241
Expression system: Escherichia coli

Quick links

Citations

34 review citations

Metabolic regulation of mitochondrial dynamics.
Mishra et al. (2016)
33 more

3 mentions without citation

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
Richter et al. (2014)
2 more