› 4nzp

X-ray diffraction
2.31Å resolution

The crystal structure of argininosuccinate synthase from Campylobacter jejuni subsp. jejuni NCTC 11168

Released:
DOI: 10.2210/pdb4nzp/pdb
PDB entry 4nzp coloured by chain, front view.
PDB entry 4nzp coloured by chain, side view.
PDB entry 4nzp coloured by chain, top view.
Source organism: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Entry authors: Tan K, Gu M, Zhang R, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192895 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Argininosuccinate synthase Chain: A
Molecule details ›
Chain: A
Length: 409 amino acids
Theoretical weight: 45.91 KDa
Source organism: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9PHK7 (Residues: 1-406; Coverage: 100%)
Gene names: Cj0665c, argG
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I222
Unit cell:
a: 64.646Å b: 97.36Å c: 141.526Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.244
Expression system: Escherichia coli BL21(DE3)

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