We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 4o5f

X-ray diffraction
1.55Å resolution

Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis in complex with pantothenate and phosphate

Released:
DOI: 10.2210/pdb4o5f/pdb
Model geometry
Fit model/data
PDB entry 4o5f coloured by chain, front view.
PDB entry 4o5f coloured by chain, side view.
PDB entry 4o5f coloured by chain, top view.
Source organism: Burkholderia thailandensis E264
Entry authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
[(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)., (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+).]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174003 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type III pantothenate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 280 amino acids
Theoretical weight: 29.32 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2T1M2 (Residues: 1-259; Coverage: 100%)
Gene names: BTH_I0369, coaX
Sequence domains: Type III pantothenate kinase
Structure domains: Nucleotidyltransferase; domain 5

Ligands and Environments

6 bound ligands:
Ligand PAU 2 x PAU
Ligand PO4 2 x PO4
Ligand ATP 2 x ATP
Ligand CL 2 x CL
Ligand GOL 3 x GOL
Ligand K 2 x K
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P43212
Unit cell:
a: 99.44Å b: 99.44Å c: 112.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.156 0.183
Expression system: Escherichia coli BL21(DE3)

Quick links