› 4oca

X-ray diffraction
2.3Å resolution

Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N

Released:
DOI: 10.2210/pdb4oca/pdb
PDB entry 4oca coloured by chain, front view.
PDB entry 4oca coloured by chain, side view.
PDB entry 4oca coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
Structural basis for substrate specificity in ArnB. A key enzyme in the polymyxin resistance pathway of Gram-negative bacteria.
Lee M, Sousa MC
Biochemistry 53 796-805 (2014)
PMID: 24460375

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Chain: A
Molecule details ›
Chain: A
Length: 385 amino acids
Theoretical weight: 41.8 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand 2QR 1 x 2QR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P43212
Unit cell:
a: 90.952Å b: 90.952Å c: 129.123Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.261
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The yin and yang of bacterial resilience in the human gut microbiota.
Gibson et al. (2014)
10 other articles

3 mentions without citation

Assessment of template-based modeling of protein structure in CASP11.
Modi et al. (2016)
2 more