› 4ofq

X-ray diffraction
1.8Å resolution

Structure of the C-terminal domain of the Streptococcus pyogenes antigen I/II-family protein AspA

Released:
DOI: 10.2210/pdb4ofq/pdb
PDB entry 4ofq coloured by chain, front view.
PDB entry 4ofq coloured by chain, side view.
PDB entry 4ofq coloured by chain, top view.
Source organism: Streptococcus pyogenes MGAS6180
Primary publication:
Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes.
Hall M, Nylander S, Jenkinson HF, Persson K
FEBS Open Bio 4 283-9 (2014)
PMID: 24918040

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175388 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gram-positive cocci surface proteins LPxTG domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 347 amino acids
Theoretical weight: 38.95 KDa
Source organism: Streptococcus pyogenes MGAS6180
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q48S75 (Residues: 971-1307; Coverage: 26%)
Gene name: M28_Spy1325
Sequence domains:
Structure domains: Immunoglobulin-like

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR-H
Spacegroup: P21212
Unit cell:
a: 99.002Å b: 104.979Å c: 74.442Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.231
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Streptococcus pyogenes biofilms-formation, biology, and clinical relevance.
Fiedler et al. (2015)
2 more

2 mentions without citation

CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks.
Echelman et al. (2016)
1 more