› 4p52

X-ray diffraction
2.6Å resolution

Crystal structure of homoserine kinase from Cytophaga hutchinsonii ATCC 33406, NYSGRC Target 032717.

Released:
DOI: 10.2210/pdb4p52/pdb
PDB entry 4p52 coloured by chain, front view.
PDB entry 4p52 coloured by chain, side view.
PDB entry 4p52 coloured by chain, top view.
Source organism: Cytophaga hutchinsonii ATCC 33406
Entry authors: Malashkevich VN, Bhosle R, Toro R, Hillerich B, Gizzi A, Garforth S, Kar A, Chan MK, Lafluer J, Patel H, Matikainen B, Chamala S, Lim S, Celikgil A, Villegas G, Evans B, Love J, Fiser A, Seidel R, Bonanno JB, Almo SC, New York Structural Genomics Research Consortium (NYSGRC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164983 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homoserine kinase Chain: A
Molecule details ›
Chain: A
Length: 331 amino acids
Theoretical weight: 35.4 KDa
Source organism: Cytophaga hutchinsonii ATCC 33406
Expression system: Escherichia coli BL21(DE3)
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P6422
Unit cell:
a: 101.608Å b: 101.608Å c: 195.982Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.172 0.209
Expression system: Escherichia coli BL21(DE3)

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