› 4p8s

X-ray diffraction
1.8Å resolution

Crystal structure of Nogo-receptor-2

Released:
DOI: 10.2210/pdb4p8s/pdb
PDB entry 4p8s coloured by chain, front view.
PDB entry 4p8s coloured by chain, side view.
PDB entry 4p8s coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of the Nogo-receptor-2.
Semavina M, Saha N, Kolev MV, Goldgur Y, Giger RJ, Himanen JP, Nikolov DB
Protein Sci 20 684-9 (2011)
PMID: 21308849

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Reticulon-4 receptor-like 2 Chain: A
Molecule details ›
Chain: A
Length: 282 amino acids
Theoretical weight: 31.94 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q80WD1 (Residues: 29-310; Coverage: 72%)
Gene names: Ngrh1, Rtn4rl2
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 56.822Å b: 56.517Å c: 128.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.205
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

The Nogo-66 receptor family in the intact and diseased CNS.
Borrie et al. (2012)
1 more