› 4p9a

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126085 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase acidic protein Chain: A
Molecule details ›
Chain: A
Length: 464 amino acids
Theoretical weight: 53.34 KDa
Source organism: Influenza A virus (A/chicken/Zhejiang/DTID-ZJU01/2013(H7N9))
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: M9V5W3 (Residues: 247-709; Coverage: 65%)
Gene name: PA
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P6522
Unit cell:
a: 68.89Å b: 68.89Å c: 400.19Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.203 0.228
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design.
Stevaert et al. (2016)
3 other articles

1 mention without citation

Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Moen et al. (2014)