› 4pbo

X-ray diffraction
1.7Å resolution

Crystal structure of zebrafish short-chain pentraxin protein without calcium ions

Released:
DOI: 10.2210/pdb4pbo/pdb
PDB entry 4pbo coloured by chain, front view.
PDB entry 4pbo coloured by chain, side view.
PDB entry 4pbo coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces.
Chen R, Qi J, Yuan H, Wu Y, Hu W, Xia C
J Struct Biol 189 259-68 (2015)
PMID: 25592778

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170966 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-reactive protein Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 23.56 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0IIP8 (Residues: 19-225; Coverage: 100%)
Gene name: crp
Sequence domains: Pentaxin family
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: R3
Unit cell:
a: 114.745Å b: 114.745Å c: 61.023Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.174 0.186
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Regulation of C-reactive protein conformation in inflammation.
Yao et al. (2019)
4 other articles

2 mentions without citation

In silico Analysis Revealed High-risk Single Nucleotide Polymorphisms in Human Pentraxin-3 Gene and their Impact on Innate Immune Response against Microbial Pathogens.
Thakur et al. (2016)
1 more