› 4pco

X-ray diffraction
1.32Å resolution

Crystal structure of double-stranded RNA with four terminal GU wobble base pairs

Released:
DOI: 10.2210/pdb4pco/pdb
PDB entry 4pco coloured by chain, front view.
PDB entry 4pco coloured by chain, side view.
PDB entry 4pco coloured by chain, top view.
Source organism: Endothia gyrosa
Primary publication:
Structures and Energetics of Four Adjacent G·U Pairs That Stabilize an RNA Helix.
Gu X, Mooers BH, Thomas LM, Malone J, Harris S, Schroeder SJ
J Phys Chem B 119 13252-61 (2015)
PMID: 26425937

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196855 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-D(*GP*GP*UP*GP*GP*CP*UP*GP*UP*U)-3') Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 10 nucleotides
Theoretical weight: 3.21 KDa
Source organism: Endothia gyrosa
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand NCO 12 x NCO
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 36.616Å b: 43.224Å c: 83.256Å
α: 90° β: 102.48° γ: 90°
R-values:
R R work R free
0.157 0.155 0.184
Expression system: Not provided

Quick links

Citations

5 citation in other articles

Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops.
Phan et al. (2017)
4 more

3 mentions without citation

The multiple flavors of GoU pairs in RNA.
Westhof et al. (2019)
2 more