Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ionotropic glutamate receptor, metazoa
- Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
- Ionotropic glutamate receptor, C-terminal
- Ionotropic glutamate receptor
- Receptor, ligand binding region
- Periplasmic binding protein-like I
- Glutamate [NMDA] receptor subunit 1-like, ligand-binding domain
- Glutamate [NMDA] receptor subunit 1-like, N-terminal LIVBP-like domain
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
NMDA receptor complex, GluN1-GluN2B (preferred)
PDBe Complex ID:
PDB-CPX-152911 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Glutamate receptor ionotropic, NMDA 1
Molecule details ›
Chains: A, C
Length: 825 amino acids
Theoretical weight: 92.68 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 825 amino acids
Theoretical weight: 92.68 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P35439 (Residues: 23-847; Coverage: 90%)
Sequence domains:
Glutamate receptor ionotropic, NMDA 2B
Molecule details ›
Chains: B, D
Length: 820 amino acids
Theoretical weight: 92.16 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 820 amino acids
Theoretical weight: 92.16 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q00960 (Residues: 27-852; Coverage: 56%)
Sequence domains:
- Receptor family ligand binding region
- Ligated ion channel L-glutamate- and glycine-binding site
- Ligand-gated ion channel
Ligands and Environments
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 23-ID-B
Spacegroup:
P21
Expression system: Spodoptera frugiperda
