› 4q2o

X-ray diffraction
2.1Å resolution

PDLIM4 PDZ in Complex with a Phage-Derived Peptide

Released:
DOI: 10.2210/pdb4q2o/pdb
PDB entry 4q2o coloured by chain, front view.
PDB entry 4q2o coloured by chain, side view.
PDB entry 4q2o coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A structural portrait of the PDZ domain family.
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS
J Mol Biol 426 3509-19 (2014)
PMID: 25158098

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156196 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PDZ and LIM domain protein 4 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 98 amino acids
Theoretical weight: 10.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P50479 (Residues: 1-84; Coverage: 26%)
Gene names: PDLIM4, RIL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P21
Unit cell:
a: 33.71Å b: 64.61Å c: 126.22Å
α: 90° β: 93.05° γ: 90°
R-values:
R R work R free
0.25 0.248 0.292
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)
9 more

1 mention without citation

Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities.
Teyra et al. (2020)