› 4qav

X-ray diffraction
2.1Å resolution

The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis

Released:
DOI: 10.2210/pdb4qav/pdb
PDB entry 4qav coloured by chain, front view.
PDB entry 4qav coloured by chain, side view.
PDB entry 4qav coloured by chain, top view.
Source organism: Neisseria meningitidis alpha14
Entry authors: Nanson JD, Forwood JK

Function and Biology Details

Reaction catalysed: 
A (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a (Z)-3-oxooctadec-11-enoyl-[acyl-carrier protein] + CO(2) + an [acyl-carrier protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111629 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] synthase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 415 amino acids
Theoretical weight: 43.18 KDa
Source organism: Neisseria meningitidis alpha14
Expression system: Escherichia coli
UniProt:
  • Canonical: C6S978 (Residues: 1-415; Coverage: 100%)
Gene names: NMO_1817, fabF
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1

Ligands and Environments

2 bound ligands:
Ligand K 2 x K
Ligand FMT 3 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P65
Unit cell:
a: 153.489Å b: 153.489Å c: 66.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.173 0.196
Expression system: Escherichia coli

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